Description

Estradiol is a kind of steroid hormone, which is the most important and biologically active hormone in estrogen. For non-pregnant women, it is mainly secreted by ovarian follicles and corpus luteum; The adrenal cortex and male testicular interstitial cells can also produce a small amount of estradiol, which is mainly produced by the placenta in pregnant women. The concentration of estradiol in the blood changes during the menstrual cycle. Most circulating estradiol combines with sex hormone binding globulin or albumin, and about 1-3% of estradiol is free. Estradiol plays an indispensable role in the development of reproductive organs and secondary sexual characteristics. Estradiol determination can monitor ovarian function and is a very useful indicator for evaluating various menstrual abnormalities. It has a high guiding significance in analyzing sexual development, causes of amenorrhea, infertility and menopause; Dynamic monitoring of estradiol level is helpful to monitor ovulation, because estradiol level reflects the maturity of follicles; when female sexual precocity occurs, estradiol levels are often higher than normal; Continuous and dynamic detection of estradiol can also be used to monitor fetal placental function during pregnancy.